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Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
BACKGROUND: Hematopoietic stem cell renewal and differentiation are regulated through epigenetic processes. The conversion of 5-methylcytosine into 5-hydroxymethylcytosine (5hmC) by ten-eleven-translocation enzymes provides new insights into the epigenetic regulation of gene expression during develo...
Autores principales: | Tekpli, Xavier, Urbanucci, Alfonso, Hashim, Adnan, Vågbø, Cathrine B., Lyle, Robert, Kringen, Marianne K., Staff, Anne Cathrine, Dybedal, Ingunn, Mills, Ian G., Klungland, Arne, Staerk, Judith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888655/ https://www.ncbi.nlm.nih.gov/pubmed/27252783 http://dx.doi.org/10.1186/s13072-016-0070-8 |
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