Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10

BACKGROUND: Almost all CpG-rich promoters in the mammalian genome are bound by the multidomain FBXL10 protein (also known as KDM2B, JHDM1B, CXXC2, and NDY1). FBXL10 is expressed as two isoforms: FBXL10-1, a longer form that contains an N-terminal histone demethylase domain with C-terminal F-box, CXX...

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Detalles Bibliográficos
Autores principales: Boulard, Mathieu, Edwards, John R., Bestor, Timothy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888662/
https://www.ncbi.nlm.nih.gov/pubmed/27252784
http://dx.doi.org/10.1186/s13072-016-0069-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888662/
https://www.ncbi.nlm.nih.gov/pubmed/27252784
http://dx.doi.org/10.1186/s13072-016-0069-1

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