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Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10
BACKGROUND: Almost all CpG-rich promoters in the mammalian genome are bound by the multidomain FBXL10 protein (also known as KDM2B, JHDM1B, CXXC2, and NDY1). FBXL10 is expressed as two isoforms: FBXL10-1, a longer form that contains an N-terminal histone demethylase domain with C-terminal F-box, CXX...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888662/ https://www.ncbi.nlm.nih.gov/pubmed/27252784 http://dx.doi.org/10.1186/s13072-016-0069-1 |