Cargando…

Evolution of a transcriptional regulator from a transmembrane nucleoporin

Nuclear pore complexes (NPCs) emerged as nuclear transport channels in eukaryotic cells ∼1.5 billion years ago. While the primary role of NPCs is to regulate nucleo–cytoplasmic transport, recent research suggests that certain NPC proteins have additionally acquired the role of affecting gene express...

Descripción completa

Detalles Bibliográficos
Autores principales: Franks, Tobias M., Benner, Chris, Narvaiza, Iñigo, Marchetto, Maria C.N., Young, Janet M., Malik, Harmit S., Gage, Fred H., Hetzer, Martin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888837/
https://www.ncbi.nlm.nih.gov/pubmed/27198230
http://dx.doi.org/10.1101/gad.280941.116