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Evolution of a transcriptional regulator from a transmembrane nucleoporin
Nuclear pore complexes (NPCs) emerged as nuclear transport channels in eukaryotic cells ∼1.5 billion years ago. While the primary role of NPCs is to regulate nucleo–cytoplasmic transport, recent research suggests that certain NPC proteins have additionally acquired the role of affecting gene express...
Autores principales: | Franks, Tobias M., Benner, Chris, Narvaiza, Iñigo, Marchetto, Maria C.N., Young, Janet M., Malik, Harmit S., Gage, Fred H., Hetzer, Martin W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888837/ https://www.ncbi.nlm.nih.gov/pubmed/27198230 http://dx.doi.org/10.1101/gad.280941.116 |
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