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Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2

Histone H3 methylation on Lys4 (H3K4me) is associated with active gene transcription in all eukaryotes. In Saccharomyces cerevisiae, Set1 is the sole lysine methyltransferase required for mono-, di-, and trimethylation of this site. Although H3K4me3 is linked to gene expression, whether H3K4 methyla...

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Detalles Bibliográficos
Autores principales: Schibler, Andria, Koutelou, Evangelia, Tomida, Junya, Wilson-Pham, Marenda, Wang, Li, Lu, Yue, Cabrera, Alexa Parra, Chosed, Renee J., Li, Wenqian, Li, Bing, Shi, Xiaobing, Wood, Richard D., Dent, Sharon Y.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888839/
https://www.ncbi.nlm.nih.gov/pubmed/27198228
http://dx.doi.org/10.1101/gad.278887.116