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Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair

To allow for sufficient time to repair DNA double-stranded breaks (DSBs), eukaryotic cells activate the DNA damage checkpoint. In budding yeast, Rad53 (mammalian Chk2) phosphorylation parallels the persistence of the unrepaired DSB and is extinguished when repair is complete in a process termed reco...

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Detalles Bibliográficos
Autores principales: Tsabar, Michael, Waterman, David P., Aguilar, Fiona, Katsnelson, Lizabeth, Eapen, Vinay V., Memisoglu, Gonen, Haber, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888841/
https://www.ncbi.nlm.nih.gov/pubmed/27222517
http://dx.doi.org/10.1101/gad.280685.116