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Brain endothelial cell‐targeted gene therapy of neurovascular disorders

Neurovascular disorders are difficult to treat due to the blood–brain barrier (BBB), which prevents delivery of most drugs from the blood into the brain. Gene therapy can potentially overcome this barrier, but classical vectors are neither efficient nor specific enough to provide long‐lasting treatm...

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Detalles Bibliográficos
Autores principales: Marchiò, Serena, Sidman, Richard L, Arap, Wadih, Pasqualini, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888850/
https://www.ncbi.nlm.nih.gov/pubmed/27189170
http://dx.doi.org/10.15252/emmm.201606407