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Chronic miR‐29 antagonism promotes favorable plaque remodeling in atherosclerotic mice

Abnormal remodeling of atherosclerotic plaques can lead to rupture, acute myocardial infarction, and death. Enhancement of plaque extracellular matrix (ECM) may improve plaque morphology and stabilize lesions. Here, we demonstrate that chronic administration of LNA‐miR‐29 into an atherosclerotic mou...

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Detalles Bibliográficos
Autores principales: Ulrich, Victoria, Rotllan, Noemi, Araldi, Elisa, Luciano, Amelia, Skroblin, Philipp, Abonnenc, Mélanie, Perrotta, Paola, Yin, Xiaoke, Bauer, Ashley, Leslie, Kristen L, Zhang, Pei, Aryal, Binod, Montgomery, Rusty L, Thum, Thomas, Martin, Kathleen, Suarez, Yajaira, Mayr, Manuel, Fernandez‐Hernando, Carlos, Sessa, William C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888854/
https://www.ncbi.nlm.nih.gov/pubmed/27137489
http://dx.doi.org/10.15252/emmm.201506031