Gene-Specific Assessment of Guanine Oxidation as an Epigenetic Modulator for Cardiac Specification of Mouse Embryonic Stem Cells

Epigenetics have essential roles in development and human diseases. Compared to the complex histone modifications, epigenetic changes on mammalian DNA are as simple as methylation on cytosine. Guanine, however, can be oxidized as an epigenetic change which can undergo base-pair transversion, causing...

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Detalles Bibliográficos
Autores principales: Park, Joonghoon, Park, Jong Woo, Oh, Hawmok, Maria, Fernanda S., Kang, Jaeku, Tian, Xiuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889044/
https://www.ncbi.nlm.nih.gov/pubmed/27249188
http://dx.doi.org/10.1371/journal.pone.0155792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889044/
https://www.ncbi.nlm.nih.gov/pubmed/27249188
http://dx.doi.org/10.1371/journal.pone.0155792

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