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Gene-Specific Assessment of Guanine Oxidation as an Epigenetic Modulator for Cardiac Specification of Mouse Embryonic Stem Cells
Epigenetics have essential roles in development and human diseases. Compared to the complex histone modifications, epigenetic changes on mammalian DNA are as simple as methylation on cytosine. Guanine, however, can be oxidized as an epigenetic change which can undergo base-pair transversion, causing...
Autores principales: | Park, Joonghoon, Park, Jong Woo, Oh, Hawmok, Maria, Fernanda S., Kang, Jaeku, Tian, Xiuchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889044/ https://www.ncbi.nlm.nih.gov/pubmed/27249188 http://dx.doi.org/10.1371/journal.pone.0155792 |
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