APOBEC4 Enhances the Replication of HIV-1

APOBEC4 (A4) is a member of the AID/APOBEC family of cytidine deaminases. In this study we found a high mRNA expression of A4 in human testis. In contrast, there were only low levels of A4 mRNA detectable in 293T, HeLa, Jurkat or A3.01 cells. Ectopic expression of A4 in HeLa cells resulted in mostly...

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Detalles Bibliográficos
Autores principales: Marino, Daniela, Perković, Mario, Hain, Anika, Jaguva Vasudevan, Ananda A., Hofmann, Henning, Hanschmann, Kay-Martin, Mühlebach, Michael D., Schumann, Gerald G., König, Renate, Cichutek, Klaus, Häussinger, Dieter, Münk, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889046/
https://www.ncbi.nlm.nih.gov/pubmed/27249646
http://dx.doi.org/10.1371/journal.pone.0155422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889046/
https://www.ncbi.nlm.nih.gov/pubmed/27249646
http://dx.doi.org/10.1371/journal.pone.0155422

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