Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense

Mycobacterium tuberculosis (Mtb) must cope with exogenous oxidative stress imposed by the host. Unlike other antioxidant enzymes, Mtb’s thioredoxin reductase TrxB2 has been predicted to be essential not only to fight host defenses but also for in vitro growth. However, the specific physiological rol...

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Detalles Bibliográficos
Autores principales: Lin, Kan, O'Brien, Kathryn M., Trujillo, Carolina, Wang, Ruojun, Wallach, Joshua B., Schnappinger, Dirk, Ehrt, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889078/
https://www.ncbi.nlm.nih.gov/pubmed/27249779
http://dx.doi.org/10.1371/journal.ppat.1005675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889078/
https://www.ncbi.nlm.nih.gov/pubmed/27249779
http://dx.doi.org/10.1371/journal.ppat.1005675

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