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The frequency of SLCO1B1*5 polymorphism genotypes among Russian and Sakha (Yakutia) patients with hypercholesterolemia

INTRODUCTION: Statins are the most commonly prescribed medicines for treatment of hypercholesterolemia. At the same time, up to 25% of patients cannot tolerate or have to discontinue the statin therapy due to statin-induced myopathy. In a majority of cases, statin-induced myopathy is attributed to S...

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Detalles Bibliográficos
Autores principales: Sychev, Dmitrij Alekseevitch, Shuev, Grigorij Nikolaevich, Chertovskih, Jana Valer’evna, Maksimova, Nadezhda Romanovna, Grachev, Andrej Vladimirovich, Syrkova, Ol’ga Aleksandrovna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889090/
https://www.ncbi.nlm.nih.gov/pubmed/27307760
http://dx.doi.org/10.2147/PGPM.S99634