Local Application of Leptin Antagonist Attenuates Angiotensin II–Induced Ascending Aortic Aneurysm and Cardiac Remodeling

BACKGROUND: Ascending thoracic aortic aneurysm (ATAA) is driven by angiotensin II (AngII) and contributes to the development of left ventricular (LV) remodeling through aortoventricular coupling. We previously showed that locally available leptin augments AngII‐induced abdominal aortic aneurysms in...

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Detalles Bibliográficos
Autores principales: Ben‐Zvi, Danny, Savion, Naphtali, Kolodgie, Frank, Simon, Amos, Fisch, Sudeshna, Schäfer, Katrin, Bachner‐Hinenzon, Noa, Cao, Xin, Gertler, Arieh, Solomon, Gili, Kachel, Erez, Raanani, Ehud, Lavee, Jacob, Kotev Emeth, Shlomo, Virmani, Renu, Schoen, Frederick J., Schneiderman, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889208/
https://www.ncbi.nlm.nih.gov/pubmed/27143353
http://dx.doi.org/10.1161/JAHA.116.003474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889208/
https://www.ncbi.nlm.nih.gov/pubmed/27143353
http://dx.doi.org/10.1161/JAHA.116.003474

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