The homologous recombination component EEPD1 is required for genome stability in response to developmental stress of vertebrate embryogenesis

Stressed replication forks can be conservatively repaired and restarted using homologous recombination (HR), initiated by nuclease cleavage of branched structures at stalled forks. We previously reported that the 5′ nuclease EEPD1 is recruited to stressed replication forks, where it plays critical e...

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Detalles Bibliográficos
Autores principales: Chun, Changzoon, Wu, Yuehan, Lee, Suk-Hee, Williamson, Elizabeth A., Reinert, Brian L., Jaiswal, Aruna Shanker, Nickoloff, Jac A., Hromas, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889227/
https://www.ncbi.nlm.nih.gov/pubmed/26900729
http://dx.doi.org/10.1080/15384101.2016.1151585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889227/
https://www.ncbi.nlm.nih.gov/pubmed/26900729
http://dx.doi.org/10.1080/15384101.2016.1151585

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