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The homologous recombination component EEPD1 is required for genome stability in response to developmental stress of vertebrate embryogenesis
Stressed replication forks can be conservatively repaired and restarted using homologous recombination (HR), initiated by nuclease cleavage of branched structures at stalled forks. We previously reported that the 5′ nuclease EEPD1 is recruited to stressed replication forks, where it plays critical e...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889227/ https://www.ncbi.nlm.nih.gov/pubmed/26900729 http://dx.doi.org/10.1080/15384101.2016.1151585 |