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PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage
PrimPol is a recently identified member of the archaeo-eukaryote primase (AEP) family of primase-polymerases. It has been shown that this mitochondrial and nuclear localized enzyme plays roles in the maintenance of both unperturbed replication fork progression and in the bypass of lesions after DNA...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889237/ https://www.ncbi.nlm.nih.gov/pubmed/26694751 http://dx.doi.org/10.1080/15384101.2015.1128597 |