Cargando…

CDKIs p18(INK4c) and p57(Kip2) are involved in quiescence of CML leukemic stem cells after treatment with TKI

Chronic Myeloid Leukemia (CML) is sustained by a small population of cells with stem cell characteristics known as Leukemic Stem Cells that are positive to BCR-ABL fusion protein, involved with several abnormalities in cell proliferation, expansion, apoptosis and cell cycle regulation. Current treat...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreno-Lorenzana, Dafne, Avilés-Vazquez, Sócrates, Sandoval Esquivel, Miguel Angel, Alvarado-Moreno, Antonio, Ortiz-Navarrete, Vianney, Torres-Martínez, Héctor, Ayala-Sánchez, Manuel, Mayani, Héctor, Chavez-Gonzalez, Antonieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889309/
https://www.ncbi.nlm.nih.gov/pubmed/26985855
http://dx.doi.org/10.1080/15384101.2016.1160976