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Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor

The haptoglobin-haemoglobin receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in the bloodstream of the mammalian host, allowing it to acquire haem through the uptake of haptoglobin-haemoglobin complexes. Here we show that in Trypanosoma congolense th...

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Detalles Bibliográficos
Autores principales: Lane-Serff, Harriet, MacGregor, Paula, Peacock, Lori, Macleod, Olivia JS, Kay, Christopher, Gibson, Wendy, Higgins, Matthew K, Carrington, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889325/
https://www.ncbi.nlm.nih.gov/pubmed/27083048
http://dx.doi.org/10.7554/eLife.13044