Cargando…
Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor
The haptoglobin-haemoglobin receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in the bloodstream of the mammalian host, allowing it to acquire haem through the uptake of haptoglobin-haemoglobin complexes. Here we show that in Trypanosoma congolense th...
Autores principales: | Lane-Serff, Harriet, MacGregor, Paula, Peacock, Lori, Macleod, Olivia JS, Kay, Christopher, Gibson, Wendy, Higgins, Matthew K, Carrington, Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889325/ https://www.ncbi.nlm.nih.gov/pubmed/27083048 http://dx.doi.org/10.7554/eLife.13044 |
Ejemplares similares
-
Structural basis for ligand and innate immunity factor uptake by the
trypanosome haptoglobin-haemoglobin receptor
por: Lane-Serff, Harriet, et al.
Publicado: (2014) -
A Receptor’s Tale: An Eon in the Life of a Trypanosome Receptor
por: Higgins, Matthew K., et al.
Publicado: (2017) -
Tyrosyl radical in haemoglobin and haptoglobin-haemoglobin complex: how does haptoglobin make haemoglobin less toxic?
por: Svistunenko, Dimitri A., et al.
Publicado: (2020) -
Variation and molecular evolution of HmbR, the Neisseria meningitidis haemoglobin receptor
por: Evans, Nicholas J., et al.
Publicado: (2010) -
Selection on embryonic haemoglobin in an elevational generalist songbird
por: Beckman, Elizabeth J., et al.
Publicado: (2022)