Hepcidin Plays a Key Role in 6-OHDA Induced Iron Overload and Apoptotic Cell Death in a Cell Culture Model of Parkinson's Disease

Background. Elevated brain iron levels have been implicated in the pathogenesis of Parkinson's disease (PD). However, the precise mechanism underlying abnormal iron accumulation in PD is not clear. Hepcidin, a hormone primarily produced by hepatocytes, acts as a key regulator in both systemic a...

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Detalles Bibliográficos
Autores principales: Xu, Qi, Kanthasamy, Anumantha G., Jin, Huajun, Reddy, Manju B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889865/
https://www.ncbi.nlm.nih.gov/pubmed/27298749
http://dx.doi.org/10.1155/2016/8684130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889865/
https://www.ncbi.nlm.nih.gov/pubmed/27298749
http://dx.doi.org/10.1155/2016/8684130

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