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Blockade of Rostral Ventrolateral Medulla (RVLM) Bombesin Receptor Type 1 Decreases Blood Pressure and Sympathetic Activity in Anesthetized Spontaneously Hypertensive Rats

Intrathecal injection of bombesin (BBS) promoted hypertensive and sympathoexcitatory effects in normotensive (NT) rats. However, the involvement of rostral ventrolateral medulla (RVLM) in these responses is still unclear. In the present study, we investigated: (1) the effects of BBS injected bilater...

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Detalles Bibliográficos
Autores principales: Pinto, Izabella S., Mourão, Aline A., da Silva, Elaine F., Camargo, Amanda S., Marques, Stefanne M., Gomes, Karina P., Fajemiroye, James O., da Silva Reis, Angela A., Rebelo, Ana C. S., Ferreira-Neto, Marcos L., Rosa, Daniel A., Freiria-Oliveira, André H., Castro, Carlos H., Colombari, Eduardo, Colugnati, Diego B., Pedrino, Gustavo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889888/
https://www.ncbi.nlm.nih.gov/pubmed/27313544
http://dx.doi.org/10.3389/fphys.2016.00205