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Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast

Understanding telomere length maintenance mechanisms is central in cancer biology as their dysregulation is one of the hallmarks for immortalization of cancer cells. Important for this well-balanced control is the transcriptional regulation of the telomerase genes. We integrated Mixed Integer Linear...

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Detalles Bibliográficos
Autores principales: Poos, Alexandra M., Maicher, André, Dieckmann, Anna K., Oswald, Marcus, Eils, Roland, Kupiec, Martin, Luke, Brian, König, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889924/
https://www.ncbi.nlm.nih.gov/pubmed/26908654
http://dx.doi.org/10.1093/nar/gkw111