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Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast
Understanding telomere length maintenance mechanisms is central in cancer biology as their dysregulation is one of the hallmarks for immortalization of cancer cells. Important for this well-balanced control is the transcriptional regulation of the telomerase genes. We integrated Mixed Integer Linear...
Autores principales: | Poos, Alexandra M., Maicher, André, Dieckmann, Anna K., Oswald, Marcus, Eils, Roland, Kupiec, Martin, Luke, Brian, König, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889924/ https://www.ncbi.nlm.nih.gov/pubmed/26908654 http://dx.doi.org/10.1093/nar/gkw111 |
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