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The human DNA ends proteome uncovers an unexpected entanglement of functional pathways

DNA ends get exposed in cells upon either normal or dysfunctional cellular processes or molecular events. Telomeres need to be protected by the shelterin complex to avoid junctions occurring between chromosomes while failing topoisomerases or clustered DNA damage processing may produce double-strand...

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Detalles Bibliográficos
Autores principales: Berthelot, Vivien, Mouta-Cardoso, Gildas, Hégarat, Nadia, Guillonneau, François, François, Jean-Christophe, Giovannangeli, Carine, Praseuth, Danièle, Rusconi, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889927/
https://www.ncbi.nlm.nih.gov/pubmed/26921407
http://dx.doi.org/10.1093/nar/gkw121