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CLASS2: accurate and efficient splice variant annotation from RNA-seq reads

Next generation sequencing of cellular RNA is making it possible to characterize genes and alternative splicing in unprecedented detail. However, designing bioinformatics tools to accurately capture splicing variation has proven difficult. Current programs can find major isoforms of a gene but miss...

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Detalles Bibliográficos
Autores principales: Song, Li, Sabunciyan, Sarven, Florea, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889935/
https://www.ncbi.nlm.nih.gov/pubmed/26975657
http://dx.doi.org/10.1093/nar/gkw158