Novel glycylated sugar alcohols protect ESC-specific microRNAs from degradation in iPS cells

Excessive accumulation of embryonic stem cell (ESC)-specific microRNAs occurs in both ESCs and induced pluripotent stem cells (iPSC); yet, the mechanism involved is unknown. In iPSCs, we for the first time found that novel glycylated sugar alcohols, particularly glycylglycerins, are tightly bound wi...

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Detalles Bibliográficos
Autores principales: Chang-Lin, Samantha, Hung, Albert, Chang, Donald C., Lin, Yi-Wen, Ying, Shao-Yao, Lin, Shi-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889939/
https://www.ncbi.nlm.nih.gov/pubmed/27001514
http://dx.doi.org/10.1093/nar/gkw186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889939/
https://www.ncbi.nlm.nih.gov/pubmed/27001514
http://dx.doi.org/10.1093/nar/gkw186

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