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Base pairing and structural insights into the 5-formylcytosine in RNA duplex

5-Formylcytidine (f(5)C), a previously discovered natural nucleotide in the mitochondrial tRNA of many species including human, has been recently detected as the oxidative product of 5-methylcytidine (m(5)C) through 5-hydroxymethylcytidine (hm(5)C) in total RNA of mammalian cells. The discovery indi...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Luo, Zhipu, He, Kaizhang, Delaney, Michael O., Chen, Doris, Sheng, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889945/
https://www.ncbi.nlm.nih.gov/pubmed/27079978
http://dx.doi.org/10.1093/nar/gkw235