Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR)

Long Interspersed Element 1 (LINE-1 or L1) is capable of causing genomic instability through the activity of the L1 ORF2 protein (ORF2p). This protein contains endonuclease (EN) and reverse transcriptase (RT) domains that are necessary for the retrotransposition of L1 and the Short Interspersed Elem...

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Detalles Bibliográficos
Autores principales: Christian, Claiborne M., deHaro, Dawn, Kines, Kristine J., Sokolowski, Mark, Belancio, Victoria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889948/
https://www.ncbi.nlm.nih.gov/pubmed/27095191
http://dx.doi.org/10.1093/nar/gkw277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889948/
https://www.ncbi.nlm.nih.gov/pubmed/27095191
http://dx.doi.org/10.1093/nar/gkw277

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