Cargando…
Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR)
Long Interspersed Element 1 (LINE-1 or L1) is capable of causing genomic instability through the activity of the L1 ORF2 protein (ORF2p). This protein contains endonuclease (EN) and reverse transcriptase (RT) domains that are necessary for the retrotransposition of L1 and the Short Interspersed Elem...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889948/ https://www.ncbi.nlm.nih.gov/pubmed/27095191 http://dx.doi.org/10.1093/nar/gkw277 |