Do nucleic acids moonlight as molecular chaperones?

Organisms use molecular chaperones to combat the unfolding and aggregation of proteins. While protein chaperones have been widely studied, here we demonstrate that DNA and RNA exhibit potent chaperone activity in vitro. Nucleic acids suppress the aggregation of classic chaperone substrates up to 300...

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Detalles Bibliográficos
Autores principales: Docter, Brianne E., Horowitz, Scott, Gray, Michael J., Jakob, Ursula, Bardwell, James C.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889950/
https://www.ncbi.nlm.nih.gov/pubmed/27105849
http://dx.doi.org/10.1093/nar/gkw291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889950/
https://www.ncbi.nlm.nih.gov/pubmed/27105849
http://dx.doi.org/10.1093/nar/gkw291

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