A putative Leishmania DNA polymerase theta protects the parasite against oxidative damage

Leishmania infantum is a protozoan parasite that is phagocytized by human macrophages. The host macrophages kill the parasite by generating oxidative compounds that induce DNA damage. We have identified, purified and biochemically characterized a DNA polymerase θ from L. infantum (LiPolθ), demonstra...

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Detalles Bibliográficos
Autores principales: Fernández-Orgiler, Abel, Martínez-Jiménez, María I., Alonso, Ana, Alcolea, Pedro J., Requena, Jose M., Thomas, María C., Blanco, Luis, Larraga, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889957/
https://www.ncbi.nlm.nih.gov/pubmed/27131366
http://dx.doi.org/10.1093/nar/gkw346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889957/
https://www.ncbi.nlm.nih.gov/pubmed/27131366
http://dx.doi.org/10.1093/nar/gkw346

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