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Newly identified motifs in Candida albicans Cdr1 protein nucleotide binding domains are pleiotropic drug resistance subfamily-specific and functionally asymmetric

An analysis of Candida albicans ABC transporters identified conserved related α-helical sequence motifs immediately C-terminal of each Walker A sequence. Despite the occurrence of these motifs in ABC subfamilies of other yeasts and higher eukaryotes, their roles in protein function remained unexplor...

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Detalles Bibliográficos
Autores principales: Rawal, Manpreet Kaur, Banerjee, Atanu, Shah, Abdul Haseeb, Khan, Mohammad Firoz, Sen, Sobhan, Saxena, Ajay Kumar, Monk, Brian C., Cannon, Richard D., Bhatnagar, Rakesh, Mondal, Alok Kumar, Prasad, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890005/
https://www.ncbi.nlm.nih.gov/pubmed/27251950
http://dx.doi.org/10.1038/srep27132