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Immuno-targeting the multifunctional CD38 using nanobody

CD38, as a cell surface antigen is highly expressed in several hematologic malignancies including multiple myeloma (MM) and has been proven to be a good target for immunotherapy of the disease. CD38 is also a signaling enzyme responsible for the metabolism of two novel calcium messenger molecules. T...

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Detalles Bibliográficos
Autores principales: Li, Ting, Qi, Shali, Unger, Mandy, Hou, Yun Nan, Deng, Qi Wen, Liu, Jun, Lam, Connie M. C., Wang, Xian Wang, Xin, Du, Zhang, Peng, Koch-Nolte, Friedrich, Hao, Quan, Zhang, Hongmin, Lee, Hon Cheung, Zhao, Yong Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890012/
https://www.ncbi.nlm.nih.gov/pubmed/27251573
http://dx.doi.org/10.1038/srep27055