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Macrophage-mediated inflammatory response decreases mycobacterial survival in mouse MSCs by augmenting NO production

Mycobacterium tuberculosis (MTB) is a hard-to-eradicate intracellular microbe, which escapes host immune attack during latent infection. Recent studies reveal that mesenchymal stem cells (MSCs) provide a protective niche for MTB to maintain latency. However, the regulation of mycobacterial residency...

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Detalles Bibliográficos
Autores principales: Yang, Kun, Wu, Yongjian, Xie, Heping, Li, Miao, Ming, Siqi, Li, Liyan, Li, Meiyu, Wu, Minhao, Gong, Sitang, Huang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890015/
https://www.ncbi.nlm.nih.gov/pubmed/27251437
http://dx.doi.org/10.1038/srep27326