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Peripheral Brain Derived Neurotrophic Factor Precursor Regulates Pain as an Inflammatory Mediator
The precursor of brain derived neurotrophic factor (proBDNF), the unprocessed BDNF gene product, binds to its receptors and exerts the opposing biologic functions of mature BDNF. proBDNF is expressed in the peripheral tissues but the functions of peripheral proBDNF remain elusive. Here we showed tha...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890020/ https://www.ncbi.nlm.nih.gov/pubmed/27251195 http://dx.doi.org/10.1038/srep27171 |