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Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine

The long noncoding RNA Gomafu/MIAT/Rncr2 is thought to function in retinal cell specification, stem cell differentiation and the control of alternative splicing. To further investigate physiological functions of Gomafu, we created mouse knockout (KO) model that completely lacks the Gomafu gene. The...

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Detalles Bibliográficos
Autores principales: Ip, Joanna Y., Sone, Masamitsu, Nashiki, Chieko, Pan, Qun, Kitaichi, Kiyoyuki, Yanaka, Kaori, Abe, Takaya, Takao, Keizo, Miyakawa, Tsuyoshi, Blencowe, Benjamin J., Nakagawa, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890022/
https://www.ncbi.nlm.nih.gov/pubmed/27251103
http://dx.doi.org/10.1038/srep27204