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miR-146a is essential for lipopolysaccharide (LPS)-induced cross-tolerance against kidney ischemia/reperfusion injury in mice

MicroRNA-146a is one of most important microRNAs involved in development of endotoxin tolerance via (toll-like receptors) TLRs/ NF-κB pathway. In this study, we sought to identify the mechanistic role of miR-146a in mediating the protective effect of lipopolysaccharide (LPS) pretreatment on kidney i...

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Detalles Bibliográficos
Autores principales: Dai, Yan, Jia, Ping, Fang, Yi, Liu, Hong, Jiao, Xiaoyan, He, John C., Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890025/
https://www.ncbi.nlm.nih.gov/pubmed/27250735
http://dx.doi.org/10.1038/srep27091