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Molecular mechanism and functional significance of acid generation in the Drosophila midgut

The gut of Drosophila melanogaster includes a proximal acidic region (~pH 2), however the genome lacks the H(+)/K(+) ATPase characteristic of the mammalian gastric parietal cell, and the molecular mechanisms of acid generation are poorly understood. Here, we show that maintenance of the low pH of th...

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Detalles Bibliográficos
Autores principales: Overend, Gayle, Luo, Yuan, Henderson, Louise, Douglas, Angela E., Davies, Shireen A., Dow, Julian A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890030/
https://www.ncbi.nlm.nih.gov/pubmed/27250760
http://dx.doi.org/10.1038/srep27242