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A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells

The most effective strategy for protection against intracellular infections such as Leishmania is vaccination with live parasites. Use of recombinant proteins avoids the risks associated with live vaccines. However, due to low immunogenicity, they fail to trigger T cell responses particularly of CD8...

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Detalles Bibliográficos
Autores principales: Maji, Mithun, Mazumder, Saumyabrata, Bhattacharya, Souparno, Choudhury, Somsubhra Thakur, Sabur, Abdus, Shadab, Md., Bhattacharya, Pradyot, Ali, Nahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890172/
https://www.ncbi.nlm.nih.gov/pubmed/27251373
http://dx.doi.org/10.1038/srep27206