Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells

Inner ear sensory epithelia contain mechanosensitive hair cells that transmit information to the brain through innervation with bipolar neurons. Mammalian hair cells do not regenerate and are limited in number. Here we investigate the potential to generate mechanosensitive hair cells from mouse embr...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Ping, Koehler, Karl R., Mikosz, Andrew M., Hashino, Eri, Holt, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890183/
https://www.ncbi.nlm.nih.gov/pubmed/27215798
http://dx.doi.org/10.1038/ncomms11508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890183/
https://www.ncbi.nlm.nih.gov/pubmed/27215798
http://dx.doi.org/10.1038/ncomms11508

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