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Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells
Inner ear sensory epithelia contain mechanosensitive hair cells that transmit information to the brain through innervation with bipolar neurons. Mammalian hair cells do not regenerate and are limited in number. Here we investigate the potential to generate mechanosensitive hair cells from mouse embr...
Autores principales: | Liu, Xiao-Ping, Koehler, Karl R., Mikosz, Andrew M., Hashino, Eri, Holt, Jeffrey R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890183/ https://www.ncbi.nlm.nih.gov/pubmed/27215798 http://dx.doi.org/10.1038/ncomms11508 |
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