Essential structural elements in tRNA(Pro) for EF-P-mediated alleviation of translation stalling

The ribosome stalls on translation of polyproline sequences due to inefficient peptide bond formation between consecutive prolines. The translation factor EF-P is able to alleviate this stalling by accelerating Pro-Pro formation. However, the mechanism by which EF-P recognizes the stalled complexes...

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Detalles Bibliográficos
Autores principales: Katoh, Takayuki, Wohlgemuth, Ingo, Nagano, Masanobu, Rodnina, Marina V., Suga, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890201/
https://www.ncbi.nlm.nih.gov/pubmed/27216360
http://dx.doi.org/10.1038/ncomms11657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890201/
https://www.ncbi.nlm.nih.gov/pubmed/27216360
http://dx.doi.org/10.1038/ncomms11657

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