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Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
Upstream open reading frames (uORFs) are ubiquitous repressive genetic elements in vertebrate mRNAs. While much is known about the regulation of individual genes by their uORFs, the range of uORF-mediated translational repression in vertebrate genomes is largely unexplored. Moreover, it is unclear w...
Autores principales: | Chew, Guo-Liang, Pauli, Andrea, Schier, Alexander F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890304/ https://www.ncbi.nlm.nih.gov/pubmed/27216465 http://dx.doi.org/10.1038/ncomms11663 |
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