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Metallothionein regulates intracellular zinc signaling during CD4(+) T cell activation
BACKGROUND: The ultra-low redox potential and zinc binding properties of the intracellular pool of mammalian metallothioneins (MT) suggest a role for MT in the transduction of redox signals into intracellular zinc signals. Increased expression of MT after exposure to heavy metals, oxidative stress,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890327/ https://www.ncbi.nlm.nih.gov/pubmed/27251638 http://dx.doi.org/10.1186/s12865-016-0151-2 |