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Metallothionein regulates intracellular zinc signaling during CD4(+) T cell activation

BACKGROUND: The ultra-low redox potential and zinc binding properties of the intracellular pool of mammalian metallothioneins (MT) suggest a role for MT in the transduction of redox signals into intracellular zinc signals. Increased expression of MT after exposure to heavy metals, oxidative stress,...

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Detalles Bibliográficos
Autores principales: Rice, James M., Zweifach, Adam, Lynes, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890327/
https://www.ncbi.nlm.nih.gov/pubmed/27251638
http://dx.doi.org/10.1186/s12865-016-0151-2