Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway

BACKGROUND: Multi-walled carbon nanotubes (MWCNT) are currently under intense toxicological investigation due to concern on their potential health effects. Current in vitro and in vivo data indicate that MWCNT exposure is strongly associated with lung toxicity (inflammation, fibrosis, granuloma, can...

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Detalles Bibliográficos
Autores principales: Polimeni, Manuela, Gulino, Giulia Rossana, Gazzano, Elena, Kopecka, Joanna, Marucco, Arianna, Fenoglio, Ivana, Cesano, Federico, Campagnolo, Luisa, Magrini, Andrea, Pietroiusti, Antonio, Ghigo, Dario, Aldieri, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890337/
https://www.ncbi.nlm.nih.gov/pubmed/27251132
http://dx.doi.org/10.1186/s12989-016-0138-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890337/
https://www.ncbi.nlm.nih.gov/pubmed/27251132
http://dx.doi.org/10.1186/s12989-016-0138-4

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