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Quantifying intrinsic and extrinsic control of single-cell fates in cancer and stem/progenitor cell pedigrees with competing risks analysis

The molecular control of cell fate and behaviour is a central theme in biology. Inherent heterogeneity within cell populations requires that control of cell fate is studied at the single-cell level. Time-lapse imaging and single-cell tracking are powerful technologies for acquiring cell lifetime dat...

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Detalles Bibliográficos
Autores principales: Cornwell, J. A., Hallett, R. M., der Mauer, S. Auf, Motazedian, A., Schroeder, T., Draper, J. S., Harvey, R. P., Nordon, R. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890426/
https://www.ncbi.nlm.nih.gov/pubmed/27250534
http://dx.doi.org/10.1038/srep27100