IgE epitope proximity determines immune complex shape and effector cell activation capacity

BACKGROUND: IgE-allergen complexes induce mast cell and basophil activation and thus immediate allergic inflammation. They are also important for IgE-facilitated allergen presentation to T cells by antigen-presenting cells. OBJECTIVE: To investigate whether the proximity of IgE binding sites on an a...

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Detalles Bibliográficos
Autores principales: Gieras, Anna, Linhart, Birgit, Roux, Kenneth H., Dutta, Moumita, Khodoun, Marat, Zafred, Domen, Cabauatan, Clarissa R., Lupinek, Christian, Weber, Milena, Focke-Tejkl, Margarete, Keller, Walter, Finkelman, Fred D., Valenta, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890651/
https://www.ncbi.nlm.nih.gov/pubmed/26684291
http://dx.doi.org/10.1016/j.jaci.2015.08.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890651/
https://www.ncbi.nlm.nih.gov/pubmed/26684291
http://dx.doi.org/10.1016/j.jaci.2015.08.055

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