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IgE epitope proximity determines immune complex shape and effector cell activation capacity

BACKGROUND: IgE-allergen complexes induce mast cell and basophil activation and thus immediate allergic inflammation. They are also important for IgE-facilitated allergen presentation to T cells by antigen-presenting cells. OBJECTIVE: To investigate whether the proximity of IgE binding sites on an a...

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Detalles Bibliográficos
Autores principales:	Gieras, Anna, Linhart, Birgit, Roux, Kenneth H., Dutta, Moumita, Khodoun, Marat, Zafred, Domen, Cabauatan, Clarissa R., Lupinek, Christian, Weber, Milena, Focke-Tejkl, Margarete, Keller, Walter, Finkelman, Fred D., Valenta, Rudolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890651/ https://www.ncbi.nlm.nih.gov/pubmed/26684291 http://dx.doi.org/10.1016/j.jaci.2015.08.055

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